References:

1.Biocompatibility -- OPM Internal Report: NAMSA Advisory Services Consulting Report, November 2006. ​

2.OPM Patent Portfolio: https://oxfordpm.com/patent-information ​

3.Bone-Like Mechanical Properties  -- Data on file at OPM. ​

4.Osteointegration Properties,-- OPM Internal Study – 2010. Data on file at OPM. ​

5.OsteoFab Surface Topography -- OPM Internal Study – 2013. Data on file at OPM. ​

6.In vitro OsteoFab cellular response -- OPM Internal Study with Yale University – 2014. Data on file at OPM. ​

7.Adamzyk, C., Kachel, P., Hoss, M., Gremse, F., Modabber, A., & Hölzle, F. et al. (2016). Bone tissue engineering using polyetherketoneketone scaffolds combined with autologous mesenchymal stem cells in a sheep calvarial defect model. Journal Of Cranio-Maxillofacial Surgery, 44(8), 985-994. doi: 10.1016/j.jcms.2016.04.012 ​

8.Roskies, M., Fang, D., Abdallah, M., Charbonneau, A., Cohen, N., & Jordan, J. et al. (2017). Three-dimensionally printed polyetherketoneketone scaffolds with mesenchymal stem cells for the reconstruction of critical-sized mandibular defects. The Laryngoscope, 127(11), E392-E398. doi: 10.1002/lary.26781 ​

9.Lin, Y., Umebayashi, M., Abdallah, M., Dong, G., Roskies, M., & Zhao, Y. et al. (2019). Combination of polyetherketoneketone scaffold and human mesenchymal stem cells from temporomandibular joint synovial fluid enhances bone regeneration. Scientific Reports, 9(1). doi: 10.1038/s41598-018-36778-2 ​

10.Wang, M., Bhardwaj, G., & Webster, T. (2017). Antibacterial properties of PEKK for orthopedic applications. International Journal Of Nanomedicine, Volume 12, 6471-6476. doi: 10.2147/ijn.s134983 ​

11.Webster, T. J., & Porteus, J. (2025). Mechanisms of decreased bacteria colonization on polyether ketone ketone (PEKK). Journal of Biomedical Nanotechnology, 21(2), 63–71. https://doi.org/10.1166/jbn.2025.3944

12.Cheng, B., Jaffee, S., Averick, S., Swink, I., Horvath, S., & Zhukauskas, R. (2020). A comparative study of three biomaterials in an ovine bone defect model. The Spine Journal, 20(3), 457-464. doi: 10.1016/j.spinee.2019.10.003​

13.Biological Responses to Metal Implants, September 2019. United States Food and Drug Administration. ​

14.OsteoFab Custom Device IFU - QMSL-1400 Rev B